Welcome to HIPPIE, a database of experimentally measured protein-protein interactions, which are scored based on the number and quality of such experiments.

You can query HIPPIE for the interaction partners of a single protein, the interactions between a list of proteins or check whether a list of interactions is in the database.

Please cite HIPPIE within any publication that makes use of this resource. Thanks!

Please query HIPPIE by a single UniProt identifier (id or accession), gene symbol or Entrez gene id

(e.g. HD_HUMAN, P42858, HTT or 3064)   



  Jun 24, 2016  HIPPIE v2.0 has been released including new data and analyses options

  Sep 01, 2015  We just released a new version of HIPPIE

  Sep 05, 2014  We released a new version of HIPPIE featuring protein-protein interaction effect prediction and many new interactions

  Oct 11, 2013  A new release of HIPPIE is available

  Jan 8, 2013    Please check out our new publication on creating tissue- and function-specific networks with HIPPIE in PLOS Computational Biology