This tool predicts subcellular location (either Nuclear, Nucleo-cytoplasmic, Cytoplasmic or Extracellular) of eukaryotic proteins using the predicted exposure value of their amino acids. Predictions with low scores (<0.4) can be taken as an indication that the sequence is in another location (e.g. Mitochondria).

For prediction, paste a FASTA sequence and corresponding residue exposure value (as provided by SABLE ) in the box below.
Click here to see an example...

>Example_Sequence
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAA
PPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKT
CPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRN
TFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGR
DRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALEL
KDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
4434525553413223410430152145332224334421221223444134112323324313523424
2422434434444344444424343412344514231102031345543432413113424301041444
0102020444225301000000023353143104103423445555432233100102443303014243
3211000121333433342021103220231033334433110000013442310012103020020242
2455445435554455554455455443454455355555455543202030304521300340241041
2433445355423533552455555445534411455554544


To learn more on how to get the residue exposure values from SABLE see the About page.