HIPPO

Evidence for the interaction between PGFRB_HUMAN and PTN11_HUMAN

Sources

Publications

  • 7691811 (Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.; Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG; 1993)
  • 12681492 (Stimulation of the alpha1A adrenergic receptor inhibits PDGF-induced PDGF beta receptor Tyr751 phosphorylation and PI 3-kinase activation.; Lin HY, Ballou LM, Lin RZ; 2003)
  • 8041791 (Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.; Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG; 1994)
  • 11266449 (Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.; Keilhack H, Müller M, Böhmer SA, Frank C, Weidner KM, Birchmeier W, Ligensa T, Berndt A, Kosmehl H, Günther B, Müller T, Birchmeier C, Böhmer FD; 2001)
  • 16189514 (Towards a proteome-scale map of the human protein-protein interaction network.; Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M; 2005)
  • 7530043 (Direct determination of the sequence recognition requirements of the SH2 domains of SH-PTP2.; Huyer G, Li ZM, Adam M, Huckle WR, Ramachandran C; 1995)
  • 8183548 (Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.; Feng GS, Shen R, Heng HH, Tsui LC, Kazlauskas A, Pawson T; 1994)
  • 7688466 (The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.; Kazlauskas A, Feng GS, Pawson T, Valius M; 1993)
  • 8119896 (Characterization of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains.; Dechert U, Adam M, Harder KW, Clark-Lewis I, Jirik F; 1994)
  • 8538796 (Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2.; Eck MJ, Pluskey S, Trüb T, Harrison SC, Shoelson SE; 1996)
  • 12614164 (Identification of protein tyrosine phosphatases associating with the PDGF receptor.; Markova B, Herrlich P, Rönnstrand L, Böhmer FD; 2003)
  • 23397142 (Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma.; Liu CH, Chen TC, Chau GY, Jan YH, Chen CH, Hsu CN, Lin KT, Juang YL, Lu PJ, Cheng HC, Chen MH, Chang CF, Ting YS, Kao CY, Hsiao M, Huang CY; 2013)

Experimental systems

TechniquePSI-MI codeScore
Reconstituted Complex1
surface plasmon resonanceMI:01071
x-ray crystallographyMI:01141
affinity technologyMI:04000.5
Two-hybridMI:00180.5
anti bait coimmunoprecipitationMI:00060.5
anti tag coimmunoprecipitationMI:00070.5
pull downMI:00960.25
enzymatic studyMI:04150.1
experimental interaction detectionMI:00450.1
in vivoMI:04930.1
in vitroMI:04920.1

other species

  • Rattus norvegicus (Rat) ( 1 )
  • Mus musculus (Mouse)