HIPPO

Evidence for the interaction between PGFRB_HUMAN and PDGFB_HUMAN

Sources

Publications

  • 11903042 (Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt.; Cartel NJ, Wang J, Post M; 2002)
  • 17981115 (Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels.; Fischer C, Jonckx B, Mazzone M, Zacchigna S, Loges S, Pattarini L, Chorianopoulos E, Liesenborghs L, Koch M, De Mol M, Autiero M, Wyns S, Plaisance S, Moons L, van Rooijen N, Giacca M, Stassen JM, Dewerchin M, Collen D, Carmeliet P; 2007)
  • 11297552 (Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.; Gilbertson DG, Duff ME, West JW, Kelly JD, Sheppard PO, Hofstrand PD, Gao Z, Shoemaker K, Bukowski TR, Moore M, Feldhaus AL, Humes JM, Palmer TE, Hart CE; 2001)
  • 16189514 (Towards a proteome-scale map of the human protein-protein interaction network.; Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M; 2005)
  • 10806482 (PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor.; Li X, Pontén A, Aase K, Karlsson L, Abramsson A, Uutela M, Bäckström G, Hellström M, Boström H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, Eriksson U; 2000)
  • 7679113 (Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor.; Fretto LJ, Snape AJ, Tomlinson JE, Seroogy JJ, Wolf DL, LaRochelle WJ, Giese NA; 1993)
  • 20577048 (Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-beta signaling in hepatic stellate cells.; Cao S, Yaqoob U, Das A, Shergill U, Jagavelu K, Huebert RC, Routray C, Abdelmoneim S, Vasdev M, Leof E, Charlton M, Watts RJ, Mukhopadhyay D, Shah VH; 2010)
  • 20534510 (Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.; Shim AH, Liu H, Focia PJ, Chen X, Lin PC, He X; 2010)

Experimental systems

TechniquePSI-MI codeScore
x-ray crystallographyMI:01141
cross-linking studyMI:00300.5
enzyme linked immunosorbent assayMI:04110.5
competition bindingMI:04050.5
coimmunoprecipitationMI:00190.5
affinity chromatography technologyMI:00040.5
pull downMI:00960.25
molecular sievingMI:00710.2
in vitroMI:04920.1
in vivoMI:04930.1

other species

  • None