HIPPO

Evidence for the interaction between TAU_HUMAN and CHIP_HUMAN

Sources

Publications

  • 16275660 (Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.; Grelle G, Kostka S, Otto A, Kersten B, Genser KF, Müller EC, Wälter S, Böddrich A, Stelzl U, Hänig C, Volkmer-Engert R, Landgraf C, Alberti S, Höhfeld J, Strödicke M, Wanker EE; 2005)
  • 14962978 (CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation.; Petrucelli L, Dickson D, Kehoe K, Taylor J, Snyder H, Grover A, De Lucia M, McGowan E, Lewis J, Prihar G, Kim J, Dillmann WH, Browne SE, Hall A, Voellmy R, Tsuboi Y, Dawson TM, Wolozin B, Hardy J, Hutton M; 2004)
  • 20466727 (A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.; Dolan PJ, Johnson GV; 2010)
  • 15447663 (U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.; Hatakeyama S, Matsumoto M, Kamura T, Murayama M, Chui DH, Planel E, Takahashi R, Nakayama KI, Takashima A; 2004)
  • 14612456 (CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival.; Shimura H, Schwartz D, Gygi SP, Kosik KS; 2003)
  • 18292230 (Akt and CHIP coregulate tau degradation through coordinated interactions.; Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, Petrucelli L; 2008)
  • 17304350 (The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins.; Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Eckman CB, Patterson C, Dickson DW, Nahman NS, Hutton M, Burrows F, Petrucelli L; 2007)
  • 23554879 (PINCH in the cellular stress response to tau-hyperphosphorylation.; Ozdemir AY, Rom I, Kovalevich J, Yen W, Adiga R, Dave RS, Langford D; 2013)
  • 23237806 (Involvement of endoplasmic reticulum stress in tauopathy.; Sakagami Y, Kudo T, Tanimukai H, Kanayama D, Omi T, Horiguchi K, Okochi M, Imaizumi K, Takeda M; 2012)
  • 23696636 (The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.; Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL; 2013)

Experimental systems

TechniquePSI-MI codeScore
filter bindingMI:00490.5
anti tag coimmunoprecipitationMI:00070.5
affinity chromatography technologyMI:00040.5
pull downMI:00960.25
enzymatic studyMI:04150.1

other species

  • None