HIPPO

Evidence for the interaction between CASP8_HUMAN and TNR6_HUMAN

Sources

Publications

  • 11101867 (The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity.; Siegel RM, Chan FK, Chun HJ, Lenardo MJ; 2000)
  • 17159907 (Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling.; Feig C, Tchikov V, Schütze S, Peter ME; 2006)
  • 15659383 (Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.; Gajate C, Mollinedo F; 2005)
  • 9208847 (Casper is a FADD- and caspase-related inducer of apoptosis.; Shu HB, Halpin DR, Goeddel DV; 1997)
  • 9325248 (Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL.; MacFarlane M, Ahmad M, Srinivasula SM, Fernandes-Alnemri T, Cohen GM, Alnemri ES; 1997)
  • 12887920 (Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes.; Micheau O, Tschopp J; 2003)
  • 11717445 (Caspase-10 is an initiator caspase in death receptor signaling.; Wang J, Chun HJ, Wong W, Spencer DM, Lenardo MJ; 2001)
  • 18328427 (Yes and PI3K bind CD95 to signal invasion of glioblastoma.; Kleber S, Sancho-Martinez I, Wiestler B, Beisel A, Gieffers C, Hill O, Thiemann M, Mueller W, Sykora J, Kuhn A, Schreglmann N, Letellier E, Zuliani C, Klussmann S, Teodorczyk M, Gröne HJ, Ganten TM, Sültmann H, Tüttenberg J, von Deimling A, Regnier-Vigouroux A, Herold-Mende C, Martin-Villalba A; 2008)
  • 16498403 (The role of receptor internalization in CD95 signaling.; Lee KH, Feig C, Tchikov V, Schickel R, Hallas C, Schütze S, Peter ME, Chan AC; 2006)
  • 10196099 (Isolation and analysis of components of CD95 (APO-1/Fas) death-inducing signaling complex.; Scaffidi C, Krammer PH, Peter ME; 1999)
  • 21625644 (Modulation of the CD95-induced apoptosis: the role of CD95 N-glycosylation.; Shatnyeva OM, Kubarenko AV, Weber CE, Pappa A, Schwartz-Albiez R, Weber AN, Krammer PH, Lavrik IN; 2011)
  • 17047155 (Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation.; Rébé C, Cathelin S, Launay S, Filomenko R, Prévotat L, L'Ollivier C, Gyan E, Micheau O, Grant S, Dubart-Kupperschmitt A, Fontenay M, Solary E; 2006)
  • 21803845 (PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo.; Tao RH, Berkova Z, Wise JF, Rezaeian AH, Daniluk U, Ao X, Hawke DH, Karp JE, Lin HK, Molldrem JJ, Samaniego F; 2011)
  • 26186194 (The BioPlex Network: A Systematic Exploration of the Human Interactome.; Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, Erickson BK, Wühr M, Chick J, Zhai B, Kolippakkam D, Mintseris J, Obar RA, Harris T, Artavanis-Tsakonas S, Sowa ME, De Camilli P, Paulo JA, Harper JW, Gygi SP; 2015)
  • 27321185 (USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability.; Jeong M, Lee EW, Seong D, Seo J, Kim JH, Grootjans S, Kim SY, Vandenabeele P, Song J; 2016)
  • 28514442 (Architecture of the human interactome defines protein communities and disease networks.; Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW; 2017)
  • 26942442 (An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers.; Chakrabandhu K, Huault S, Durivault J, Lang K, Ta Ngoc L, Bole A, Doma E, Dérijard B, Gérard JP, Pierres M, Hueber AO; 2016)
  • 21713032 (The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.; Tauzin S, Chaigne-Delalande B, Selva E, Khadra N, Daburon S, Contin-Bordes C, Blanco P, Le Seyec J, Ducret T, Counillon L, Moreau JF, Hofman P, Vacher P, Legembre P; 2011)
  • 20956295 (Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema.; Chen ZH, Lam HC, Jin Y, Kim HP, Cao J, Lee SJ, Ifedigbo E, Parameswaran H, Ryter SW, Choi AM; 2010)

Experimental systems

TechniquePSI-MI codeScore
Affinity Capture-Western0.5
coimmunoprecipitationMI:00190.5
affinity chromatography technologyMI:00040.5
anti bait coimmunoprecipitationMI:00060.5
cosedimentation through density gradientMI:00290.2
copurificationMI:00250.2
in vivoMI:04930.1
colocalization by immunostainingMI:00220.1
imaging techniqueMI:04280.1

other species

  • Mus musculus (Mouse) ( 1 )