HIPPO

Evidence for the interaction between IL3RB_HUMAN and JAK2_HUMAN

Sources

Publications

  • 10772872 (SH2-Containing protein tyrosine phosphatase-1 (SHP-1) association with Jak2 in UT-7/Epo cells.; Wu DW, Stark KC, Dunnington D, Dillon SB, Yi T, Jones C, Pelus LM; 2000)
  • 7775438 (The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain.; Zhao Y, Wagner F, Frank SJ, Kraft AS; 1995)
  • 7527392 (Convergence of signaling by interleukin-3, granulocyte-macrophage colony-stimulating factor, and mast cell growth factor on JAK2 tyrosine kinase.; Brizzi MF, Zini MG, Aronica MG, Blechman JM, Yarden Y, Pegoraro L; 1994)
  • 18692472 (The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.; Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, Ramshaw H, Woodcock JM, Xu Y, Guthridge M, McKinstry WJ, Lopez AF, Parker MW; 2008)
  • 16437163 (Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.; Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF; 2006)
  • 21965659 (Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signaling.; Lei JT, Mazumdar T, Martinez-Moczygemba M; 2011)

Experimental systems

TechniquePSI-MI codeScore
Reconstituted Complex1
Affinity Capture-Western0.5
affinity chromatography technologyMI:00040.5
anti bait coimmunoprecipitationMI:00060.5
pull downMI:00960.25
in vivoMI:04930.1

other species

  • None