HIPPO

Evidence for the interaction between GHR_HUMAN and JAK2_HUMAN

Sources

Publications

  • 7540178 (Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor.; Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, Sakai I, Kraft AS; 1995)
  • 10502458 (The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver.; Hellgren G, Jansson JO, Carlsson LM, Carlsson B; 1999)
  • 8063815 (Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.; VanderKuur JA, Wang X, Zhang L, Campbell GS, Allevato G, Billestrup N, Norstedt G, Carter-Su C; 1994)
  • 21347402 (Jak2 is a negative regulator of ubiquitin-dependent endocytosis of the growth hormone receptor.; Putters J, da Silva Almeida AC, van Kerkhof P, van Rossum AG, Gracanin A, Strous GJ; 2011)
  • 24280222 (Multimeric growth hormone receptor complexes serve as signaling platforms.; Sedek M, van der Velden LM, Strous GJ; 2013)

Experimental systems

TechniquePSI-MI codeScore
Affinity Capture-Western0.5
affinity chromatography technologyMI:00040.5
in vivoMI:04930.1

other species

  • None