HIPPO

Evidence for the interaction between TAU_HUMAN and KS6A3_HUMAN

Sources

Publications

  • 9546672 (Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.; Zheng-Fischhöfer Q, Biernat J, Mandelkow EM, Illenberger S, Godemann R, Mandelkow E; 1998)
  • 11311121 (The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.; Woods YL, Cohen P, Becker W, Jakes R, Goedert M, Wang X, Proud CG; 2001)
  • 9353289 (Phosphorylation by neuronal cdc2-like protein kinase promotes dimerization of Tau protein in vitro.; Paudel HK; 1997)
  • 11181841 (Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry.; Lund ET, McKenna R, Evans DB, Sharma SK, Mathews WR; 2001)
  • 9832145 (New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry.; Hanger DP, Betts JC, Loviny TL, Blackstock WP, Anderton BH; 1998)
  • 12387894 (Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta.; Liu F, Iqbal K, Grundke-Iqbal I, Gong CX; 2002)
  • 17512525 (Phosphorylation of human microtubule-associated protein tau by protein kinases of the AGC subfamily.; Virdee K, Yoshida H, Peak-Chew S, Goedert M; 2007)

Experimental systems

TechniquePSI-MI codeScore
protein kinase assayMI:04240.75
in vitroMI:04920.1
enzymatic studyMI:04150.1

other species

  • None