HIPPO

Evidence for the interaction between TERT_HUMAN and AKT1_HUMAN

Sources

Publications

  • 10224060 (Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit.; Kang SS, Kwon T, Kwon DY, Do SI; 1999)
  • 15843522 (IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.; Kawauchi K, Ihjima K, Yamada O; 2005)
  • 18775701 (Pectenotoxin-2 represses telomerase activity in human leukemia cells through suppression of hTERT gene expression and Akt-dependent hTERT phosphorylation.; Kim MO, Moon DO, Kang SH, Heo MS, Choi YH, Jung JH, Lee JD, Kim GY; 2008)
  • 28628118 (OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc.; Ivanov AA, Gonzalez-Pecchi V, Khuri LF, Niu Q, Wang Y, Xu Y, Bai Y, Mo X, Prochownik EV, Johns MA, Du Y, Khuri FR, Fu H; 2017)

Experimental systems

TechniquePSI-MI codeScore
fluorescent resonance energy transferMI:00550.6
Affinity Capture-Western0.5
affinity chromatography technologyMI:00040.5
anti bait coimmunoprecipitationMI:00060.5
in vitroMI:04920.1
in vivoMI:04930.1

other species

  • None