HIPPO

Evidence for the interaction between PTEN_HUMAN and P53_HUMAN

Sources

Publications

  • 12620407 (PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms.; Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, Lesche R, Whale AD, Martinez-Diaz H, Rozengurt N, Cardiff RD, Liu X, Wu H; 2003)
  • 16713569 (A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.; Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY; 2006)
  • 14559824 (PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells.; Zhou M, Gu L, Findley HW, Jiang R, Woods WG; 2003)
  • 24141722 (p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.; Hong SW, Moon JH, Kim JS, Shin JS, Jung KA, Lee WK, Jeong SY, Hwang JJ, Lee SJ, Suh YA, Kim I, Nam KY, Han S, Kim JE, Kim KP, Hong YS, Lee JL, Lee WJ, Choi EK, Lee JS, Jin DH, Kim TW; 2013)
  • 18339852 (PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations.; Li Y, Guessous F, Kwon S, Kumar M, Ibidapo O, Fuller L, Johnson E, Lal B, Hussaini I, Bao Y, Laterra J, Schiff D, Abounader R; 2008)

Experimental systems

TechniquePSI-MI codeScore
Affinity Capture-Western0.5
affinity chromatography technologyMI:00040.5
pull downMI:00960.25
in vitroMI:04920.1
in vivoMI:04930.1

other species

  • None