HIPPO

Evidence for the interaction between P63_HUMAN and P53_HUMAN

Sources

Publications

  • 11238924 (A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain.; Gaiddon C, Lokshin M, Ahn J, Zhang T, Prives C; 2001)
  • 19345189 (A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis.; Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, Solari A, Bobisse S, Rondina MB, Guzzardo V, Parenti AR, Rosato A, Bicciato S, Balmain A, Piccolo S; 2009)
  • 16713569 (A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.; Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY; 2006)
  • 21741598 (A Pin1/mutant p53 axis promotes aggressiveness in breast cancer.; Girardini JE, Napoli M, Piazza S, Rustighi A, Marotta C, Radaelli E, Capaci V, Jordan L, Quinlan P, Thompson A, Mano M, Rosato A, Crook T, Scanziani E, Means AR, Lozano G, Schneider C, Del Sal G; 2011)
  • 23687300 (15-hydroxyprostaglandin dehydrogenase-derived 15-keto-prostaglandin E2 inhibits cholangiocarcinoma cell growth through interaction with peroxisome proliferator-activated receptor-γ, SMAD2/3, and TAP63 proteins.; Lu D, Han C, Wu T; 2013)
  • 22575646 (Cell density-dependent acetylation of ΔNp63α is associated with p53-dependent cell cycle arrest.; Chae YS, Kim H, Kim D, Lee H, Lee HO; 2012)
  • 25417702 (Functional interplay between MDM2, p63/p73 and mutant p53.; Stindt MH, Muller PA, Ludwig RL, Kehrloesser S, Dötsch V, Vousden KH; 2014)
  • 24554706 (The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins.; Wei S, Wang H, Lu C, Malmut S, Zhang J, Ren S, Yu G, Wang W, Tang DD, Yan C; 2014)

Experimental systems

TechniquePSI-MI codeScore
affinity chromatography technologyMI:00040.5
anti bait coimmunoprecipitationMI:00060.5
in vivoMI:04930.1

other species

  • Mus musculus (Mouse)