Evidence for the interaction between NGF_HUMAN and NTRK1_HUMAN
Sources
br>Publications
br>- 10490030 (Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.; Wiesmann C, Ultsch MH, Bass SH, de Vos AM; 1999)
- 14985763 (Sortilin is essential for proNGF-induced neuronal cell death.; Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, Hempstead BL, Petersen CM; 2004)
- 11729324 (Regulation of cell survival by secreted proneurotrophins.; Lee R, Kermani P, Teng KK, Hempstead BL; 2001)
- 10713102 (TrkA amino acids controlling specificity for nerve growth factor.; O'Connell L, Hongo JA, Presta LG, Tsoulfas P; 2000)
- 1849459 (The trk proto-oncogene encodes a receptor for nerve growth factor.; Klein R, Jing SQ, Nanduri V, O'Rourke E, Barbacid M; 1991)
- 9857023 (A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals.; Saragovi HU, Zheng W, Maliartchouk S, DiGugliemo GM, Mawal YR, Kamen A, Woo SB, Cuello AC, Debeir T, Neet KE; 1998)
- 9083066 (Two restricted sites on the surface of the nerve growth factor molecule independently determine specific TrkA receptor binding and activation.; Kullander K, Kaplan D, Ebendal T; 1997)
- 11738045 (Specificity in Trk receptor:neurotrophin interactions: the crystal structure of TrkB-d5 in complex with neurotrophin-4/5.; Banfield MJ, Naylor RL, Robertson AG, Allen SJ, Dawbarn D, Brady RL; 2001)
Experimental systems
br>Technique | PSI-MI code | Score |
---|---|---|
surface plasmon resonance | MI:0107 | 1 |
Reconstituted Complex | 1 | |
x-ray crystallography | MI:0114 | 1 |
Co-crystal Structure | 1 | |
cross-linking study | MI:0030 | 0.5 |
pull down | MI:0096 | 0.25 |
molecular sieving | MI:0071 | 0.2 |
in vitro | MI:0492 | 0.1 |
in vivo | MI:0493 | 0.1 |
other species
br>- None