Evidence for the interaction between CASP8_HUMAN and BAP31_HUMAN



  • 9334338 (p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum.; Ng FW, Nguyen M, Kwan T, Branton PE, Nicholson DW, Cromlish JA, Shore GC; 1997)
  • 12668660 (Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol.; Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC; 2003)
  • 11917123 (The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum.; Breckenridge DG, Nguyen M, Kuppig S, Reth M, Shore GC; 2002)
  • 21183955 (Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction.; Iwasawa R, Mahul-Mellier AL, Datler C, Pazarentzos E, Grimm S; 2010)
  • 15254227 (Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death.; Chandra D, Choy G, Deng X, Bhatia B, Daniel P, Tang DG; 2004)

Experimental systems

TechniquePSI-MI codeScore
Reconstituted Complex1
anti bait coimmunoprecipitationMI:00060.5
Affinity Capture-Western0.5
affinity chromatography technologyMI:00040.5
Biochemical Activity0.5
pull downMI:00960.25
enzymatic studyMI:04150.1
in vivoMI:04930.1

other species

  • None