Evidence for the interaction between IRAK4_HUMAN and TLR4_HUMAN



  • 21220427 (Endotoxin tolerance impairs IL-1 receptor-associated kinase (IRAK) 4 and TGF-beta-activated kinase 1 activation, K63-linked polyubiquitination and assembly of IRAK1, TNF receptor-associated factor 6, and IkappaB kinase gamma and increases A20 expression.; Xiong Y, Qiu F, Piao W, Song C, Wahl LM, Medvedev AE; 2011)
  • 21829704 (TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.; Sakaguchi M, Murata H, Yamamoto K, Ono T, Sakaguchi Y, Motoyama A, Hibino T, Kataoka K, Huh NH; 2011)

Experimental systems

TechniquePSI-MI codeScore
affinity chromatography technologyMI:00040.5
anti tag coimmunoprecipitationMI:00070.5

other species

  • None